Trending Federal Contract Opportunities: September 16, 2026

These ten open federal contract opportunities were the most researched by the G2X community over the last 24 hours. The roundup spans current market-research requests and active solicitations for defense systems, conservation monitoring, health research, and space technology.

1. Army CASTLE KEEP development and sustainment

Army Contracting Command–Aberdeen Proving Ground is gathering capability information for HQDA G-2’s CASTLE KEEP portal. The system supports Sensitive Compartmented Information program reporting, metrics, information sharing, and automated workflows across the Army.

The anticipated work combines software development and sustainment in Army commercial cloud environments with cybersecurity testing and integration. Cleared personnel and appropriate secure workspaces are central to the requirement. Businesses of all sizes may respond to Sources Sought solicitation W56KGY26CKRFI0001 through September 22 at noon Eastern.

Sources

SAM.gov — SAM.gov.

Detailed opportunity overview — G2X.

2. NRCS easement change detection

USDA’s Natural Resources Conservation Service seeks a system for detecting changes on conservation easements using satellite and aerial imagery. The National Easement Monitoring System would help staff identify possible changes, apply configurable alert thresholds, and review properties through regularly refreshed basemaps.

The scope covers users across all 50 states, along with training and support for national monitoring workflows. USDA’s Procurement Operations Division acquisition-management office in Fort Collins is conducting the purchase for NRCS. Solicitation 12314426Q0307 is a total small-business set-aside, with quotations due September 21.

Sources

SAM.gov — SAM.gov.

Detailed opportunity overview — G2X.

B01 12314426Q0307 RFQ.pdf — SAM.gov.

3. Navy enterprise cloud and network operations

NAVSUP Fleet Logistics Center Norfolk is accepting proposals for enterprise cloud support services supporting Naval Network Warfare Command. The requirement covers the operations behind Navy cloud, network, collaboration, and endpoint services, including environments handling controlled and classified information.

Work includes cloud administration at Impact Levels 5 and 6, software-defined networking, Microsoft 365 services, and records-management and eDiscovery support. The scope connects day-to-day service operations with the security and integration needs of a defense enterprise. Solicitation N0018926RL011 is a total small-business set-aside, with proposals due October 13.

Sources

SAM.gov — SAM.gov.

Detailed opportunity overview — G2X.

Performance Work Statement.pdf — SAM.gov.

Solicitation - N0018926RL011.pdf — SAM.gov.

QASP AND QASP MATRIX.pdf — SAM.gov.

WD 2015-4341 REV 36 DATED 8.22.26.pdf — SAM.gov.

4. FDA nicotine-pouch and tobacco-use data analysis

FDA’s Center for Tobacco Products needs rapid analysis of nicotine-pouch and electronic nicotine-delivery-system use among young people. The requirement draws on existing continuous surveys and national cohorts to examine brands, purchasing behavior, and patterns of use.

The work centers on recurring reports, wave-based analysis, and additional requests as research questions emerge. It is an analysis service built around existing data, rather than a new clinical trial. FDA’s Office of Acquisition and Grants Services is handling solicitation 75F40126Q00407, with responses due September 18.

Sources

SAM.gov — SAM.gov.

Detailed opportunity overview — G2X.

RFQ_75F40126Q00407_Final.docx — SAM.gov.

5. Marine Corps cyberspace support and AI integration

Marine Corps Systems Command’s Portfolio Acquisition Executive for Mission Systems is gathering information on support for the Marine Corps Cyberspace Environment. The requirement combines enterprise IT operational support with exploration of AI-enabled automation.

Qualified personnel remain the core of the proposed service, while AI integration is intended to support the work of cyberspace operations teams. The Sources Sought notice seeks industry input on capabilities and approaches before a later acquisition decision. Responses to solicitation M6785426I4208 are due October 5.

Sources

SAM.gov — SAM.gov.

Detailed opportunity overview — G2X.

RFI M67854-26-I-4208.docx — SAM.gov.

RFI M67854-26-I-4208 Amendment 01.docx — SAM.gov.

Attachment 1 - Vendor Comment Matrix_M67854-26-I-4208.xlsx — SAM.gov.

Attachment 2- Industry QA Matrix_V1 M67854-26-I-4208 Amendment 01.xlsx — SAM.gov.

6. DCSA personnel-security alert management

The Defense Counterintelligence and Security Agency is seeking information on a Personnel Security Alert Management platform for its trusted-workforce mission. The proposed system would bring alerts from more than 40 data sources into a common environment for prioritization and human review.

The scope includes privacy-preserving tokenization, explainable risk ranking, open interfaces, and integration with existing case-management systems. DCSA is examining capabilities resembling security-information and event-management and security-operations platforms, adapted to personnel-security workflows. This is a market-research RFI, solicitation DCSAPSAMRFI2026001, with responses due September 22.

Sources

SAM.gov — SAM.gov.

Detailed opportunity overview — G2X.

RFI_DCSA PSAM_RFI_20260914.docx — SAM.gov.

7. NASA SBIR Phase II technology white papers

NASA is requesting white papers from companies with SBIR Phase II technologies that could help reduce risk for agency programs. The exercise maps existing technologies to NASA priorities and identifies firms interested in further development through a potential Sequential Phase II award.

The current call is for programmatic planning, not a funding competition. NASA may later invite proposals, with outreach notionally anticipated in January 2027. Amendment 2 extends the white-paper deadline for solicitation 80NSSC26R0014 to September 16 at 11 a.m. Eastern.

Sources

SAM.gov — SAM.gov.

Detailed opportunity overview — G2X.

Amendment to change Close date.pdf — SAM.gov.

NASA 2026 Sequential Call for White Papers Update Close date.pdf — SAM.gov.

NASA 2026 Sequential Call for White Papers 8.12.26.pdf — SAM.gov.

8. CDC poliovirus-containment framework

The Interior Business Center’s Acquisition Services Directorate is purchasing technical support for CDC’s Office of Readiness and Response. The work would establish a U.S.-led biorisk-management framework for poliovirus containment, including standards mapping, implementation resources, stakeholder engagement, and workforce training.

The scope brings together ISO 35001, WHO guidance, and NIH design requirements. It also identifies ANSI as the only vendor with the specific licenses and technical services needed for the described ISO-aligned certification program. Responses to solicitation 140D0426R0119 are due September 16.

Sources

SAM.gov — SAM.gov.

Detailed opportunity overview — G2X.

Attachment_1_SOW_Biorisk_Managment_Framework.pdf — SAM.gov.

B08_SOL_-_RFP_CDC_Biorisk_final.pdf — SAM.gov.

9. VA enterprise radiotherapy quality assurance

VA’s Technology Acquisition Center in New Jersey is seeking a contractor-hosted radiotherapy quality-assurance system and repository for VA Radiation Oncology Centers. The software would combine manually entered and automatically collected QA data and integrate with existing imaging, treatment-planning, and treatment-delivery equipment.

The solution must satisfy applicable VA security authorization and FedRAMP requirements before processing VA data. The purchase includes a base year and four option years. Solicitation 36C10B26Q0804 is a total small-business set-aside; Amendment 2 moves the quotation deadline to September 18.

Sources

SAM.gov — SAM.gov.

Detailed opportunity overview — G2X.

36C10B26Q0804 Amendment 0001.docx — SAM.gov.

36C10B26Q0804 Amendment 0002.docx — SAM.gov.

Radiotherapy Questions and Answers 9.10.26.docx — SAM.gov.

36C10B26Q0804 Final.docx — SAM.gov.

10. Marine Corps communications-system engineering support

Naval Information Warfare Center Atlantic is gathering capability information for its United States Marine Corps Communication Systems Integrated Product Team. The proposed work spans systems engineering, software, cybersecurity, program management, and logistics supporting Marine Corps communications capabilities.

The Sources Sought notice is directed to small businesses holding a SeaPort NxG multiple-award contract. Its draft structure includes a base period and four annual options. This is market research rather than a request for proposals, with responses to solicitation N65236-26-RFPREQ-LSUBP00004-0005 due October 2.

Sources

SAM.gov — SAM.gov.

Detailed opportunity overview — G2X.

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